Personal, Indoor and Outdoor Particulate Air Pollution and Heart Rate Variability in Elderly Subjects with Coronary Artery Disease
نویسنده
چکیده
............................................................................................................................ v EXECUTIVE SUMMARY ........................................................................................................ vi BODY OF REPORT ................................................................................................................ 8 1. Chapter One: Introduction ............................................................................................. 8 1.1 Background ................................................................................................................ 8 1.2. Scope and Purpose of the Project ............................................................................ 11 1.3. Tasks ........................................................................................................................ 14 2. Chapter Two: Task 1 .................................................................................................... 23 2.0 Introduction .................................................................................................................... 23 2.1 Materials and Methods ............................................................................................. 23 2.1.1 Study Population. .................................................................................................. 23 2.1.2 Ambulatory Data: Electrocardiograph and Personal Accelerometer. .................... 24 2.1.3 Exposures ............................................................................................................ 26 2.1.4 Statistical Analysis ............................................................................................... 29 2.2. Results ....................................................................................................................... 30 2.2.1 Descriptive Data ................................................................................................... 30 2.2.2 Results of the Regression Analyses ..................................................................... 36 2.2.3 Effect modification of air pollutant effects on HRV by medication use .................. 53 2.3 Discussion ..................................................................................................................... 55 2.4 Summary and Conclusions .......................................................................................... 57 References ........................................................................................................................... 57
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